Schilling test (STD tests)

Schilling test

Definition

The Schilling test is used to determine whether the body absorbs vitamin B12 normally.

Alternative Names

Vitamin B12 absorption test

Why the Schilling test is Performed

The Schilling test is performed to check vitamin B12 absorption.

Intrinsic factor is produced in the stomach and is required for vitamin B12 absorption. If your body does not make intrinsic factor, you cannot absorb vitamin B12. The lack of intrinsic factor can lead to low levels of vitamin B12 because of pernicious anemia, partial removal of the stomach (gastrectomy), poor vitamin B12 absorption due to bowel disease, too much bacteria in the intestine, a lack of enough enzymes being produced by the pancreas, or certain medications. The Schilling test is most commonly used to evaluate patients for pernicious anemia.

The test can be falsely positive. Most of the time this is due to poor urine collection. Other reasons include kidney disease or problems with the lining of the small intestine.

More about medical testing.